IFNγ: Issuing macrophages a license to kill
نویسنده
چکیده
T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNgamma.
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 204 شماره
صفحات -
تاریخ انتشار 2007